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7475050 |
Systems for developing analytical device methods
Systems and processes for using the same for developing analytical device methods are provided. Also provided are computer program products for executing the subject processes.
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7473367 |
Monolithic column
Permeable polymeric monolithic materials are prepared in a plastic column casing. In one embodiment, the permeable polymeric monolithic materials are polymerized by the application of heat from an...
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7473366 |
Process for the purification of macrolides
The invention relates to a process for the recovery of a macrolide in substantial pure form including:
a) treating an impure or crude macrolide with water immiscible solvent to form a mixture, b)...
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7473354 |
Recycled suppressor regenerants
A suppressed ion chromatographic apparatus using a regenerant recycle loop, comprising (a) an ion separation device, (b) a membrane suppressor, (c) a detector, (d) a container for regenerant...
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7468130 |
Organosilanes and substrates covalently bonded with same and methods for synthesis and use same
The present invention provides novel silicon compounds, methods for making these novel silicon compounds, compositions comprising these novel silicon compounds attached to substrates, methods for...
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7462280 |
Liquid chromatography chip with flexible interface
A liquid chromatography chip may include an analytical column. After an analyte has traveled through an analytical column defined by the chromatography chip, the analyte is routed, either directly...
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7452471 |
Automated packing system and method for chromatography columns
A column packing system comprises a control unit provided with software for monitoring the column interior pressure and/or flow through the column for use in calculating the breakpoint where a...
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7452464 |
Chromatography column
A chromatography column having a longitudinal axis and comprising a column wall with a first end and a second end, a first end plate assembly removably connectable to said first end of the column...
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7449116 |
Methods and systems for protein separation
The present disclosure relates to a system and method for protein separation including: fractionating a mixture of proteins on a reversed-phase superficially porous stationary phase at a...
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7442299 |
Ion exchange porous resins for solid phase extraction and chromatography
Embodiments of the present invention are directed to porous resins for solid phase extractions. The resins feature at least one hydrophobic component, at least one hydrophilic component and at...
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7438806 |
Affinity matrices with enhanced visibility for molecular pull-down and immunoprecipitation applications
An affinity matrix for use in affinity based molecular pull down and immunoprecipitation procedures. The affinity matrix comprises a polymeric support, a dye attached to a fraction of the polymeric...
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7435865 |
Method for separating hydrocarbons and use of a zeolite therefor
A method for separating a mixture of hydrocarbons into fractions enriched in linear, mono-branched, or multi-branched hydrocarbons is disclosed. In particular, mono-branched alkanes are separated...
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7435350 |
Intelligent system and method for automated packing of chromatography columns
The present invention provides an automated system and method for packing chromatography columns. In one embodiment, the system first determines the type of media that is present in the column, and...
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7431842 |
Method of using silicon carbide for removal of adventitious agents
A method of using silicon carbide for removing adventitious materials such as endotoxins, prions, viruses and bacteria from water, buffers, aqueous solutions or biological preparations of DNA or...
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7431841 |
Method for the extraction of components made from organic material
The invention relates to a method for the extraction of components made from organic material, comprising the step of extraction with a single-phase mixture of 50 to 90 vol. % methanol and 50 to 10...
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7427358 |
Process for the recovery of tyrosol and hydroxytyrosol from oil mill wastewaters and catalytic oxidation method in order to convert tyrosol in hydroxytyrosol
A for preparing Tyrosol and/or Hydroxytyrosol from oil mill wastewaters. includes:
a) Microfiltration (MF), Ultrafiltration (UF). Nanofiltration (NF) and Reverse Osmosis (RO) of the OMW;...
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7425263 |
Multi-component, simultaneous, independent multi-gradient system for liquid chromatography
Systems and methods for separating charged molecules on the basis of their differential electrostatic binding to a charged stationary phase comprise controlling the creation of simultaneous...
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7419831 |
Method and apparatus for determination of water and for normal phase liquid chromatography
A method for calibrating an analysis instrument, e.g., a gas chromatograph, for water analysis that includes four steps. The first step is to continuously remove water from a liquid that contains...
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7419817 |
Scalable purification of AAV2, AAV4 or AAV5 using ion-exchange chromatography
The present invention provides methods of purifying adeno-associated virus (AAV) particles. These AAV particles include AAV2, AAV4 and AAV5 particles. The present invention also provides AAV...
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7419599 |
Automated packing system and method for chromatography columns
A column packing system comprises a control unit provided with software for calculating the breakpoint where a movable adapter comes into contact with a settled bed of bed media. The calculated...
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7419598 |
Chromatographic solvent monitor
A bubbler is positioned within a solvent reservoir of a chromatographic system with its opening near the bottom of the system to measure the pressure of solvent. The bubbler may use air or may use...
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7416698 |
Molecular topological fractionation of macromolecules
A process for characterizing a sample comprising a population of linear macromolecules of interest ( 104 ) and a population of long chain branched macromolecules of interest ( 103 ), the process...
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7413659 |
Liquid chromatographic method and system
To form a smooth gradient and a preparatory liquid chromatographic system having a plurality of syringe type pumps, solvents are alternately drawn and inserted into each cylinder. The solvents are...
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7413658 |
Separation method
The present invention relates to a method for separating products from a mixture by reversed phase high performance liquid chromatography using a column packed with a stationary phase which is...
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7410587 |
Liquid handling for filtration and preparative chromatography
A method and system are provided for high-precision separation of pharmaceutical or biotechnology liquids. The separation can be in accordance with direct flow filtration, tangential flow...
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7410586 |
Purification or work-up on ionic liquids by means of adsorptive separation processes
Process for the work-up of a mixture comprising ionic liquids and a further substance, wherein the substance present is separated off by means of adsorptive separation processes.
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7410571 |
Flash chromatography cartridge
A low pressure liquid chromatographic cartridge is provided having a tubular polymer container adapted to receive a chromatographic packing material. The container has an outlet port located at a...
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7407576 |
Separating agent for an optical enantiomeric isomer
The present invention is to provide a method of producing a separating agent for an enantiomeric isomer having a high optical resolution power together with sufficient solvent resistance. That is,...
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7407568 |
Method of using sol-gel coatings for on-line preconcentration of amino acids in capillary electrophoresis
A novel on-line method is presented for the extraction and preconcentration of amino acids using a sol-gel coated column coupled to a conventional UV/vis detector. Extraction, stacking and focusing...
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7404893 |
Chromatography cartridge and method for manufacturing a chromatography cartridge
A chromatography cartridge. In some embodiments, the chromatography cartridge can include a tubular housing defining a longitudinal axis and including a relatively non-laser-writable first portion,...
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7402283 |
Electrolytic eluent generator and method of use
An acid or base is generated in an aqueous solution by the steps of:
(a) providing a source of first ions adjacent an aqueous liquid in a first acid or base generation zone, separated by a...
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7402251 |
Chromatography column and method of operation
A chromatography column is normally filled with a slurry of media for operation. A piston normally compacts the slurry in the column. The piston moves through a cavity in communication with both a...
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7402250 |
Equipment and method for feeding liquid gradient in nano/micro liquid chromatography
It is an object of the present invention to improve the performance of gradient liquid transfer in nano/micro liquid chromatographs when solvents are mixed. In a gradient liquid transfer device...
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7402243 |
Organosilanes and substrate bonded with same
The present invention provides novel silicon compounds, methods for making these novel silicon compounds, compositions comprising these novel silicon compounds attached to substrates, methods for...
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7399415 |
Parking a sample stream and suppressing the sample
Pretreatment method and apparatus to remove matrix ions from a liquid sample, prior to separation of the sample analytes (e.g. by chromatography), by flowing the liquid sample into a sample...
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7399410 |
Chromatographic column and methods for controlling sorbent density
Disclosed herein are apparatus and methods for mitigating column bed compression over time. This invention provides for an improved column design and method of controlling bed density in a...
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7399409 |
Packing material for separation of optical isomer and method of separating optical isomer with the same
The objectives of this invention are to provide a filler for separating optical isomers, capable of efficiently carrying out optical resolution of optical isomer mixtures, and to provide a process...
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7396688 |
Mass spectrometric analysis of biopolymers
The present invention makes use of unique tags of a specific biopolymer that can be exploited for determining the concentration the biopolymer in crude solutions. In preferred embodiments the...
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7396469 |
Backflow prevention for high pressure gradient systems
Gradient performance with high pressure gradient solvent delivery system is optimized by approximation of infinite stroke volume of high pressure pumps by the addition of pulse dampening with...
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7396468 |
Methods and system for protein separation
The present disclosure relates to a system and method for membrane protein separation including: fractionating a membrane sample on a reversed-phase superficially porous stationary phase at a...
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7396467 |
Method of preparing a chromatography matrix
The present invention relates to a method of preparing a porous cross-linked polysaccharide chromatography matrix, which comprises to provide an aqueous solution of a gellable polysaccharide,...
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7393453 |
Method for analysis of perchlorate
A method for analyzing the content of perchlorate in a sample matrix comprising the steps of extracting the sample matrix and applying it to a reverse phase column, followed by elution with a...
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7386427 |
Method for correcting the effects of interdetector band broadening
Chromatographic separations are often characterized by multiple detectors through which the sample flows serially. As the sample flows between detectors, it becomes progressively diluted due to...
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7384546 |
Multi-layered macromolecules and methods for their use
Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of...
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7381327 |
Flash chromatography cartridge
A low pressure liquid chromatographic cartridge is provided having a tubular polymer container adapted to receive a chromatographic packing material. The container has an outlet port located at a...
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7374724 |
Device for processing samples, use of the device, and method for producing the device
The invention relates to a device ( 1 ) for processing samples ( 2 ), comprising a body ( 3 ) with a collecting chamber ( 4 ), which can be connected with a pump ( 5 ) for aspirating, or dispensing...
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7374684 |
Method of separating components in a sample using silane-treated silica filter media
The present invention provides methods for separating one or more components of interest from a sample containing particulates and soluble materials. The method comprises the steps of: (a)...
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7374673 |
Channeled polymer fibers as stationary/support phases for chemical separation by liquid chromatography and for waste stream clean-up
Polymer fibers having a novel cross-sectional geometry are used as stationary phase materials for liquid chromatography separations. Fibers of 20 to 50 micrometer diameters have surface-channel...
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7364656 |
Triazine-based detoxification agents and their use
An affinity ligand-matrix conjugate comprises the matrix and conjugated thereto by the group Z, a ligand having general formula (I):
wherein one X is N and the other X is N, CCL or CCn; A 1 ...
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7364655 |
Method and apparatus for injecting a sample into a chromatography system
A method and apparatus for injecting a sample into a chromatography system. The apparatus can include a tubular housing having an inner surface and an open end, and a cap coupled to the open end of...
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