Matches 1 - 50 out of 108 1 2 3 >
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7416731 Human hairless antibodies  
The novel nucleotide sequence and deduced amino acid sequence of the human Hairless gene and protein, respectively, are disclosed. A Hairless expression construct may be used in transcription...
7410801 Lambda phage display system and the process  
The present invention relates to a process of obtaining recombinant lambdoid bacteriophage with high density display of functional peptides and proteins on surface of said phage comprising of:...
7408037 Tumor antigen  
Tumor antigen inducing and/or activating HLA-A2-restricted tumor-specific cytotoxic T lymphocytes that is activated by recognizing HLA-A2 and a tumor antigen peptide, and a peptide or polypeptide...
7407936 Use of copolymer 1 and related peptides and polypeptides and T cells treated herewith for neuroprotective glaucoma therapy  
Methods are provided for treating injury to or disease of the central or peripheral nervous system. In one embodiment, treatment is effected by administering activated T cells that recognize an...
7407807 Chimaeric human papillomavirus 16 I1 virus like particles and a method for preparing the particles  
The invention describes a method for producing a chimaeric human papillomavirus (HPV) L1 polypeptide containing a heterologous peptide, and in particular, a HPV L2 peptide. The method comprises the...
7407658 Vaccines for blocking transmission of plasmodium vivax  
The present invention relates novel methods and compositions for blocking transmission of Plasmodium vivax which cause malaria. In particular, Pvs25 and Pvs28 polypeptides, variants, including...
7407657 T-cell epitope peptides  
The T-cell epitope site on a Japanese cypress (hinoki) pollen allergen molecule has been identified by stimulating a T-cell line established from a patient suffering from Japanese cypress pollen...
7405039 Viral variants with altered susceptibility to nucleoside analogs and uses thereof  
The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the...
7404958 Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics  
The invention provides isolated polypeptide and nucleic acid sequences derived from Streptococcus pneumoniae that are useful in diagnosis and therapy of pathological conditions; antibodies...
7404957 Modified IL-4 mutein receptor antagonists  
This invention relates to modified IL-4 mutein receptor antagonists comprising an IL-4 mutein receptor antagonist coupled to polyethylene glycol. Related formulations and dosages and methods of...
7404270 Tumor antigen  
Tumor antigen inducing and/or activating HLA-A2-restricted tumor-specific cytotoxic T lymphocytes that is activated by recognizing HLA-A2 and a tumor antigen peptide, and a peptide or polypeptide...
7402315 Hepatitis-C virus type 4, 5 and 6  
The present invention relates to a polynucleic acid composition comprising or consisting of at least one polynucleic acid containing 8 or more contiguous nucleotides corresponding to a nucleotide...
7402314 In vivo activation of tumor-specific cytotoxic T cells  
The present invention relates to methods and compositions of activating cytotoxic T lymphocytes (CTLs) in vivo with specificity for particular antigenic peptides, and to methods and compositions of...
7399827 Page-4, an x-linked gage-like gene expressed in normal and neoplastic prostate, testis and uterus, and uses therefor  
PAGE-4 is a gene preferentially expressed in normal male and female reproductive tissues, prostate, testis, fallopian tube, uterus and placenta, as well as in prostate cancer, testicular cancer and...
7399473 Virus coat protein/receptor chimeras and method of use  
The invention relates to chimeric molecules comprising a virus coat sequence and a receptor sequence that can inter-act with each other to form a complex that is capable of binding a co-receptor....
7396811 Subcellular targeting of therapeutic proteins  
Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds...
7396533 Polypeptides and nucleic acids encoding same  
DNAs are provided, whose genes are induced at least by Wnt-1. Also provided are nucleic acid molecules encoding those polypeptides, as well as vectors and host cells comprising those nucleic acid...
7396531 Preventive and therapeutic use of polypeptides from African Swine virus as vaccines  
The present invention relates to the use of selected polypeptides from African Swine virus for the prevention and therapy of African Swine infections as well as other infections, including immune...
7393927 Protein belonging to the TNF superfamily involved in signal transduction, nucleic acids encoding same, and methods of use thereof  
A method of modulating immune response in an animal is disclosed. Such a method interacting the immature dendritic cells from the animal with an antigen ex vivo so that the immature dendritic cells...
7393921 Prostate-specific polypeptide pamp and encoding nucleic acid molecules  
The present invention relates to novel prostate specific nucleic acid molecules and polypeptides and related methods for diagnosing or predicting susceptibility to a prostate neoplastic condition.
7393831 Peptide compositions and their use against HCV  
The invention relates to novel peptide compositions. In particular, the invention relates to a peptide composition comprising at least two peptides which are selected from among the following...
7393540 Mycobacterial antigens expressed during latency  
A method is provided for identifying mycobacterial genes that are induced or up-regulated under culture conditions that are nutrient-starving and which maintain mycobacterial latency, said...
7393539 Mycobacterial antigens expressed under low oxygen tension  
A method is provided for identifying mycobacterial genes that are induced or up-regulated under continuous culture conditions defined by a dissolved oxygen tension of up to 10% air saturation...
7393536 Group B Streptococcus antigens and corresponding DNA fragments  
The present invention relates to antigens, more particularly antigens of Group B Streptococcus (GBS) ( S. agalactiae ) which may be useful to prevent, diagnose and/or treat streptococcal infections.
7393534 Compositions and methods for immunotherapy of cancer and infectious diseases  
The present invention provides compositions and methods for the prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases, for stimulating an immune response in...
7390879 Secreted and transmembrane polypeptides and nucleic acids encoding the same  
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
7390873 Antimicrobial cationic peptides  
A novel class of cationic peptides having antimicrobial activity is disclosed. These peptides can be encompassed by the formulas: X 1 X 1 PX 2 X 3 X 2 P(X 2 X 2 P) n X 2 X 3 (X 5 ) 0 ; (SEQ ID...
7390872 NF-κB peptides designed to disrupt NEMO oligomerization  
The present invention relates to polypeptides that inhibit the NF-κB signaling pathway and polynucleotides encoding the same. The present invention further provides methods for the modulation of...
7390483 Universal GM-CSF expressing bystander human K562 cell line  
The present invention provides a universal immunomodulatory cytokine-expressing bystander cell line, a composition comprising such a cell line and a cancer antigen, a method of making such a cell...
7387780 Soluble interleukin-20 receptor  
A soluble receptor to IL-20 having two polypeptide subunits, IL-20RA (formerly called ZcytoR7) and IL-20RB (formerly called DIRS1). The two subunits are preferably linked together. In one...
7387779 Anti-angiogenic proteins and fragments and methods of use thereof  
Proteins with anti-angiogenic properties are disclosed, and fragments thereof, and methods of using those proteins and fragments to inhibit or promote angiogenesis.
7387778 Therapeutic methods and compositions for the treatment of impaired interpersonal and behavioral disorders  
The invention relates to the field of psychopharmacology. More particularly, the invention relates to the treatment of mental disorders, such as impaired interpersonal and behavioral disorders,...
7384636 Polypeptide  
The present invention provides a polypeptide inducing the production of an antibody in permucosal administration in the presence of no immunological adjuvant, a composition containing the...
7384635 Protein variants of naturally occurring allergens  
The present invention relates to novel recombinant protein variants that are useful as immunotherapeutic components. Also the present invention relates to DNA sequences encoding said protein...
7381411 Aglyco products and methods of use  
Glycoconjugates, therapeutic compositions containing the glycoconjugates and therapeutic methods of using the glycoconjugates are disclosed. In particular, peptide constituents of aglyco 10B, which...
7378098 CXC chemokine receptor 4 agonist peptides  
In accordance with various aspects of the invention, CXCR4 agonists, including SDF-1 polypeptides and SDF-1 polypeptide homologues, may be used in reducing the rate of hematopoietic cell...
7375091 HER-2/neu fusion proteins  
The present invention is generally directed to HER-2/neu fusion proteins, nucleic acid molecules encoding HER-2/neu fusion proteins, viral vectors expressing HER-2/neu fusion proteins, and...
7375086 Modulators of Nod2 signaling  
The present invention relates to intracellular signaling molecules, in particular the Nod2 protein and nucleic acids encoding the Nod2 protein. The present invention provides methods of identifying...
7374766 Compositions containing virus-like particles as immunopotentiators administered through the mucosa  
The present invention is related to the branch of medicine, particularly to the new formulations of vaccine antigens. The technical objective pursued with the present invention is, precisely, the...
7374765 Methods and compositions for diagnosis and treatment of iron misregulation diseases  
Methods and compositions are provided for the diagnosis and treatment of iron misregulation diseases, including HFE polypeptides, agonists, and antagonists, and transferrin receptor agonists and...
7374764 CD33-like protein  
The present invention concerns a novel CD33-like protein. In particular, isolated nucleic acid molecules are provided encoding the CD33-like protein. Recombinant CD33-like polypeptides are also...
7374763 Protein sequences containing antigenized antibodies for foot-and-mouth disease  
Protein sequences encoding antigenized antibodies for treatment of foot-and-mouth disease (FMD) or foot-and-mouth disease virus (FMDV) of swine is provided. The antigenized antibodies are created...
7371809 Pharmacologically active antiviral peptides  
This invention relates to peptides having antiviral properties. The antiviral peptides comprise membrane transiting peptides, and active fragments and derivatives of such peptides. The antiviral...
7371388 Treatment of Sjogren's syndrome by administration of TR18 polypeptides  
The present invention relates to TR18 polypeptides. In particular, isolated nucleic acid molecules are provided encoding human TR18 protein. TR18 polypeptides are also provided as are vectors, host...
7368537 Subunit vaccine against respiratory syncytial virus infection  
The present invention relates generally to methods of treating or preventing RSV infections, and more specifically, to compositions, and the use thereof, comprising one or more RSV G protein...
7368533 Polypeptide autoantigens associated with endometriosis  
This invention provides a polynucleotide encoding Repro-EN-1.0 and IB1, polypeptides associated with endometriosis. Auto-antibodies against Repro-EN-1.0 and IB1 have been found in subjects...
7368261 Conserved Neisserial antigens  
To ensure maximum cross-strain recognition and reactivity, regions of proteins that are conserved between different Neisserial species, serogroups and strains can be used. The invention provides...
7368119 Compositions and methods for WT1 specific immunotherapy  
Compositions and methods for the therapy of malignant diseases, such as leukemia and cancer, are disclosed. The compositions comprise one or more of a WT1 polynucleotide, a WT1 polypeptide, an...
7365156 PRO1316 polypeptides  
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
7365155 Immunoregulator  
The invention relates to the field of immunology, more specifically to the field of immune-mediated disorders such as allergies, auto-immune disease, transplantation-related disease or inflammatory...
Matches 1 - 50 out of 108 1 2 3 >