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7615235 |
Film-shaped or wafer-shaped pharmaceutical preparation with masked taste
The invention relates to thin film-shaped or wafer-shaped pharmaceutical preparations for oral administration of active substances. The preparations contain at least one matrix-forming polymer...
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7595065 |
Breath freshening and oral cleansing products with synergistic combinations of magnolia bark extract and essential oils
An oral composition for oral cleansing, breath freshening, and anti-microbial benefits includes an oral cavity delivery agent and an antimicrobial active agent including a synergistic combination...
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7585519 |
Esters of L-carnitine or alkanoyl L-carnitines useful as cationic lipids for the intracellular delivery of pharmacologically active compounds
Esters of L-carnitine and alkanoyl L-carnitines are described which can be used as cationic lipids for the intracellular delivery of pharmacologically active compounds. New esters of L-carnitine...
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7579019 |
Pharmaceutical carrier device suitable for delivery of pharmaceutical compounds to mucosal surfaces
The present invention relates to a pharmaceutical delivery device for application of a pharmaceutical to mucosal surfaces. The device comprises an adhesive layer and a non-adhesive backing layer,...
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7571727 |
Molded foam mouthguard
A mouthguard includes two sections, a vertical component and a horizontal component. The foam is molded into a configuration such that the vertical component curves around the anterior section of...
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7507420 |
Peptidyl prodrugs and linkers and stabilizers useful therefor
The present invention provides analogues of duocarmycins that are potent cytotoxins. Also provided are peptidyl and disulfide linkers that are cleaved in vivo. The linkers are of use in forming...
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7491694 |
Dental restorative materials
The present invention relates to a composition for dental restoration including a dental restorative material and an effective amount of a casein phosphopeptide(CPP)-amorphous calcium phosphate...
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7482378 |
Physiological cooling compositions
The present invention provides, in one aspect, a physiological cooling composition comprising at least one cyclohexane carboxamide, at least one acyclic carboxamide, and at least one stereoisomer...
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7481995 |
Aerosol composition
An aerosol composition comprising a propellant and a first particulate material comprising particles having a median aerodynamic diameter with the range 0.05 to 11 μm, such as a medicament...
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7470397 |
Disintegratable films for diagnostic devices
The invention provides disintegratable film compositions for diagnostic test devices. The films are prepared with a combination of components that yield films of sufficient film strength and...
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7399466 |
Method and compositions for promoting osteogenesis
The object of the present invention is to increase PHEX activity to improve the osteogenic process in a mammal where this process has been diminished due to pathology or a condition that require...
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7393544 |
Dispersion for pulmonary delivery of a bioactive agent
Stabilized dispersions are provided for the delivery of a bioactive agent. The dispersions preferably comprise a plurality of perforated microstructures dispersed in a suspension medium that...
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7347985 |
Breath freshening and oral cleansing product with magnolia bark extract
A pullulan-free edible film composition for oral cleansing, breath freshening, and anti-microbial benefits includes a film forming agent and Magnolia Bark Extract. In a treatment process, an...
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7338664 |
Color changing matrix as wear indicator
A sustained-release matrix for dental application includes either an anti-microbial agent or a colorant that is released from the matrix when the matrix contacts water. The preferred matrices...
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7332230 |
Multilayer preparation in film form, consisting of hydrophilic polymers, for the rapid release of active ingredients
A multilayer preparation in the form of films of hydrophilic polymers for rapid release of substances present in the film layers into liquid surroundings is characterized in that adjacent layers...
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7332177 |
Method and formulation for treating resistance to antihypertensives and related conditions
A method for the prevention or treatment of symptoms of hypertension in a patient who is resistant to antihypertensive effects of an antihypertensive compound administered in the absence of...
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7323161 |
Patch for tooth whitening
The patch for tooth whitening of the present invention includes a tooth-adhering layer ( 1 ) containing erodible polymer complexes formed by hydrogen bonding of a polymer with a carboxyl group...
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7323160 |
Method of treating a patient's teeth using fluoride releasing glass composition
A method of treating sensitive teeth includes (1) attaching a fluoride releasing glass composition to a person's tooth, and (2) allowing fluoride to be slowly released over time in order to reduce...
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7304030 |
Matrix protein composition for dentin regeneration
The present invention relates to the surprising finding that enamel matrix, enamel matrix derivatives and/or enamel matrix proteins induce dentin regeneration. The invention thus relates to the use...
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7259139 |
Means for maintenance and/or correction of glucose concentration in blood
The invention relates to preparations that are useful in maintaining mammalian blood glucose concentrations. These preparations contain insulin, and a polymeric matrix. The polymeric matrix has a...
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7235248 |
Pharmaceutical compositions comprising cyclosporins
Pharmaceutical compositions comprising a cyclosporin, e.g. Ciclosporin or [Nva] 2 -Ciclosporin, in “microemulsion pre-concentrate” and microemulsion form. The compositions typically comprise...
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7223416 |
Topical composition
A composition containing at least one NSAID formulated for topical administration to a mucous membrane and/or skin for prophylactic or symptomatic therapy. The composition may also contain an...
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7182964 |
Dissolving thin film xanthone supplement
A nutraceutical composition containing xanthones for oral ingestion is disclosed. The composition is a rapidly dissolving film comprising water soluble polymers and xanthones. The xanthones are,...
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7175833 |
Glass composition
A glass composition having the general empirical formula given below, expressed in weight percent of the element: P: 16–24, F: 5–30, O: 20–40 and at least one of Na, K, Li or Al in an amount...
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7153511 |
Avian herpesvirus-based recombinant Infectious Bursal Disease vaccine
The present invention provides an avian recombinant herpesvirus modified by the presence of the cDNA encoding, the VP2 of the Delaware Variant E strain of IBDV, a subtype of IBDV serotype 1...
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7138135 |
Bioadhesive, closed-cell foam film, sustained release, delivery devices and methods of making and using same
Bioadhesive, closed-cell foam film, sustained release, delivery devices for administering an active agent or combination of active agents to a subject are provided. Methods for making such delivery...
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7128899 |
Bleaching device comprising a barrier layer and a bleaching composition comprising polyvinylpyrrolidone
A dental bleaching composition comprises a dental bleaching agent and a polyvinylpyrrolidone thickening agent. The bleaching composition may include water, flavoring agents, a basic substance and...
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7097851 |
Oral formulation for gastrointestinal drug delivery
An oral formulation for gastrointestinal drug delivery which comprises an adhesion site-controlling layer for attaching the formulation to the selected site in the digestive tract, a drug-carrying...
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7087249 |
Treatment of mucosal membranes
The invention relates to the use of one or more antimicrobial metals preferably selected from silver, gold, platinum, and palladium but most preferably silver, formed with atomic disorder, and...
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7087241 |
Compositions and methods for minimizing adverse drug experiences associated with oxybutynin therapy
The present invention provides compositions and methods for administering oxybutynin while minimizing the incidence and or severity of adverse drug experiences associated with oxybutynin therapy....
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7074426 |
Methods and drug delivery systems for the treatment of orofacial diseases
This invention relates to methods of treating various orofacial diseases involving inflammation, infection and/or pain, using intratissue controlled release drug delivery systems. More...
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7070800 |
Inhalable powder containing tiotropium
The invention relates to powdered preparations containing tiotropium for inhalation, processes for preparing them as well as their use in preparing a pharmaceutical composition for the treatment of...
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7070799 |
Method for administering insulin to the buccal region
A mixed micellar pharmaceutical formulation includes a micellar proteinic pharmaceutical agent, an alkali metal C8 to C22 alkyl sulfate, alkali metal salicylate, a pharmaceutically acceptable...
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7045140 |
Therapeutic delivery of carbon monoxide
Metal carbonyls are used to deliver CO having biological activity, for example vasodilatation and inhibition of transplant rejection. The metal of the carbonyl is typically of groups 7 to 10, e.g....
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7033606 |
Pharmaceutical composition intended in particular for the prevention and the treatment of radiomucositis and chemomucositis
The invention concerns a pharmaceutical composition designed to adhere to a mucous membrane for preventing or treating radiotherapy-related and chemotherapy-related mucositis, induced by...
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7030102 |
Highly bioavailable coenzyme Q-10 cyclodextrin complex
The present invention is based on the unexpected discovery that CoQ-10 can be made commercially in a highly bioavailable form suitable for topical, sublingual formulations, or for oral ingestion....
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7029690 |
Oral fluid absorbing compositions and system for application thereof in a method of dental arch treatment
Disclosed are articles and oral compositions which enable positioning material(s) which absorb oral fluids into controlled, direct contact with at least one dental arch, or portion thereof, of a...
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7025992 |
Pharmaceutical formulations
The invention relates to pharmaceutical formulations for use in the administration of lipophilic medicaments via mucosal surfaces. In particular the invention provides pharmaceutical formulations...
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7025983 |
Fast dissolving orally consumable films
Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan...
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7018622 |
Structures and compositions increasing the stability of peroxide actives
A peroxide product is provided. The peroxide product includes a package having a headspace, a substrate disposed within the package, and a thin layer of a composition having a peroxide active and a...
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7011845 |
β-glucans encapsulated in liposomes
Liposomes encapsulating a β-glucan have an improved activity of enhancing a cellular immunity, especially when they are transmucosally administered. Thus, the liposomes are useful for the...
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7005142 |
Veterinary delivery systems and methods of delivering effective agents to animals
A veterinary delivery system in the form of a pliable film comprising at least one binder, at least one lubricant, at least one solvent for the binder and lubricant, and an effective amount of at...
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7001609 |
Mucosal originated drug delivery systems and animal applications
The present invention is directed to mucosal originated drug delivery systems and methods for using the drug delivery system to treat conditions in animals. Conditions amenable to treatment...
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6998110 |
Buccal, polar and non-polar spray or capsule
Buccal aerosol sprays or capsule using polar and non-polar solvent have now been developed which provide biologically active compounds for rapid absorption through the oral mucosa, resulting in...
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6994869 |
Nasogastric enteral formulations
The present invention relates to a nasogastric formulation comprising an amino acid source, a carbohydrate source, a lipid source, and a fatty acid delivery agent wherein the fatty acid has a bond...
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6977083 |
Bioadhesive tablet containing testosterone/testosterone ester mixtures and method for producing a predetermined testosterone time-release profile with same
The method of making a bioadhesive tablet for controlling testosterone blood level, especially in elderly men suffering from partial androgen deficiency, includes spray-drying an alcoholic solution...
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6974594 |
Method of preparing biological materials and preparations produced using same
Methods for preparing products containing moisture-sensitive materials, including biological materials such as proteins, peptides or live cells, comprising at least the steps: (i) providing a...
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RE38912 |
Process for preparing powder formulations
The invention relates to a new process for producing powdered preparations for inhalation.
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6969511 |
Synthetic bulk laxative
A synthetic bulk laxative which comprises a crosslinked graft polymer. It is formed of a hydrophilic monomer partially neutralized up to 75%, a polysaccharide gum up to 3% by weight and a...
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6962717 |
Pharmaceutical compositions
A pharmaceutical composition for slow release of active ingredient in the gastrointestinal tract, comprising a plurality of active ingredient-containing particles coated with a material insoluble...
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