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7192962 |
Xanthine phosphodiesterase V inhibitor polymorphs
Crystalline polymorphs of 1-ethyl-3,7-dihydro-8-[(1R,2R) -(hydroxycyclopentyl)amino]-3-(2-hydroxyethyl)-7-[(3-bromo-4
-methoxyphenyl)methyl]-1H-Purine-2,6-dione in Form 1 and Form 2, which exhibit...
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7097859 |
Indium supplement compositions and methods therefor
A tablet for oral administration of nutritional indium comprises about 10–50 mg indium sulfate, about 4–20 mg caffeine, about 2–10% by weight cocoa powder, and about 5–10% by weight ethyl...
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7063865 |
Composition and method for substantially reducing the deleterious effects of alcohol on the body
A composition that will substantially reduce the deleterious effects of alcohol on the body and substantially reduce the side effects associated with hangovers (i.e. headaches, dizziness, nausea,...
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6953583 |
Use of conjugated linoleic acid (CLA) for the topical treatment of cellulite
The present invention relates to the use of conjugated linoleic acid (CLA) for the topical treatment of fatty deposits and cellulite and to new topical compositions and to cosmetic and...
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6949558 |
Enhancement of taxane-based chemotherapy by a CDK1 antagonist
The present invention provides a combination therapy for inhibiting the growth of tumor, for treating cancer, and for inducing cell death. The therapy comprises the sequential administration of...
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6861062 |
Skin cream
A skin cream is presented which reduces wrinkles upon topical application to the skin. The main ingredients of the composition include water and a xanthine based compound composition which is mixed...
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6821979 |
Synergistic enhancement of cognitive ability
The present invention relates to the combination of a methylxanthine and a carbonic anhydrase activator to provide synergistic effects. The invention further relates to the improved/enhanced...
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6818647 |
Method and composition for restoring diuretic and renal function
Methods and compositions for restoring diuretic and renal function.
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6776994 |
Fungicidal active compound combinations
There are described new active compound combinations of a compound of the formula (I) with known fungicidal active compounds, and their use for the control of phytopathogenic fungi.
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6713463 |
Methods and compositions for treating and preventing mucositis
A method of reducing or inhibiting mucositis in a patient, which includes administering an inflammatory cytokine inhibitor or a mast cell inhibitor, or a combination thereof, is disclosed.
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6677360 |
Biphenyl and biphenyl-analogous compounds as integrin antagonists
The present invention relates to biphenyl and biphenyl-analogous compounds, their preparation and use as pharmaceutical compositions, as integrin antagonists and in particular for the production of...
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6635677 |
Methoxyamine combinations in the treatment of cancer
This invention generally relates to novel compositions and methods for the treatment of certain cancers. Additionally, this invention relates to novel compositions and methods to screen drugs for...
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6514980 |
Nucleoside analogs in combination therapy of herpes simplex infections
A pharmaceutical product comprising a nucleoside analogue active against herpes simplex virus, such as acyclovir/valaciclovir or penciclorivir/famciclovir, and an immunosuppressant, as a combined...
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6503950 |
Triple drug therapy for the treatment of narcotic and alcohol withdrawal symptoms
A triple drug, pharmaceutical kit, composition, and method of treatment containing a combination of effective amounts of at least one anxiolytic agent, at least one centrally acting alpha...
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6503916 |
Treatment of ischemic brain injury
A composition and method adapted for the treatment of ischemic brain injury is disclosed, which includes applying hypothermic conditions to a subject within 5 hours after onset of brain injury and...
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6503915 |
Composition and method for treatment of cerebral ischemia
A composition and method for the treatment of cerebral ischemia is disclosed, the composition is a mixture of caffeine and alcohol and is used to treat cerebral ischemia by administering to a...
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6469015 |
Pharmaceutical formulation
An oil-in-water topical pharmaceutical formulation or an aqueous formulation for the treatment of virus infections of the skin or mucosa, comprising at least 30% of propylene glycol and solubilized...
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6462051 |
Composition for reducing mental fatigue, composition for maintaining and enhancing concentration, and composition for maintaining and enhancing mental vigor
The present invention is intended to provide compositions which exert excellent effects allowing improvement in the mental function of humans and animals other than humans, such as reduction of...
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6451850 |
Bio-chemical germanium complexes with high therapeutic efficiency and wide application spectrum
The present invention applies to medicine, more specifically, to pharmacology and it can be applied for the expansion of therapeutic effects spectrum, strengthening of therapeutic effect and a...
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6448227 |
Therapeutically effective substance mixture
A substance mixture, containing S-acetyl glutathione and Aciclovir, is effective as a medication against the Herpes Simplex virus and the Varicella Zoster virus.
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6447818 |
Compositions containing compounds with adrenergic activity and vegetable extracts of Crataegus and gingko biloba for the treatment of overweight and obesity
Compositions containing compounds with adrenergic activity and an extract of Crataegus standardized in flavonoids, combined with an extract of Gingko biloba standardized in flavonglucosides in...
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6440983 |
Compositions and methods for relieving headache symptoms in aspirin-sensitive headache sufferers
The treatment of migraine and/or cluster headaches in human beings in need of such treatment includes oral administration of a composition containing acetaminophen, ibuprofen, caffeine and...
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6440980 |
Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs
The present invention is related to antiviral compositions comprising long-chain aliphatic compounds in combination with a nucleoside analog or phosphonoformic acid, in a pharmaceutically...
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6436946 |
Xanthine-containing compositions for oral administration and uses related thereto
There are disclosed compositions for oral administration of a novel pharmaceutical composition, which includes xanthine-based stimulants, various neurotransmitter precursors, minerals, nootropic...
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6433022 |
Spermicide
There is provided a method of contraception, comprising exposing a spermicidally sufficient quantity of an agent to spermatozoa. The agent is a quinone represented by the following formula: Each...
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6399654 |
Biflavanoids and derivatives thereof as antiviral agents
Substantially purified antiviral biflavanoids robustaflavone, hinokiflavone, amentoflavone, agathisflavone, volkensiflavone, morelloflavone, rhusflavanone, succedaneaflavanone, GB-1a, and GB-2a are...
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6361792 |
Lipid dispersions and methods of use
Methods for preventing or ameliorating the transient adverse physiological response to particulate dispersions (TAPR response) when these dispersions are administered parenterally to a patient. The...
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6326374 |
Compositions comprising GABA analogs and caffeine
Compositions that comprise a GABA analog, such as gabapentin or pregabalin in combination with caffeine are disclosed. The compositions are used to treat pain in mammals.
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6316435 |
Combination therapy for lymphoproliferative diseases
Disclosed are methods and kits for treating lymphoproliferative diseases in a host including (co)administering to the host pentostatin, at least one alkylating agent and at least one methylated...
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RE37234 |
Nitrosated and nitrosylated phosphodiestrase inhibitor compounds, compositions and their uses
Disclosed are nitrosated and/or nitrosylated phosphodiesterase inhibitors having the formula NO n -PDE inhibitor where n is 1 or 2. The invention also provides compositions comprising such...
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6239166 |
Compositions for killing dust mites and methods of using same
The invention relates to an aqueous pesticide composition for killing dust mites, which contains a chelating agent as the active ingredient and a surfactant to facilitate distribution over, or...
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6180133 |
Antioxidant composition for topical/transdermal prevention and treatment of wrinkles
An anti-wrinkle skin treating composition comprises a pressure sensitive matrix patch having dissolved in the adhesive a mixture of antioxidants in the form of a Vitamins C ester and Vitamin E....
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6117857 |
Pharmaceutical composition
The invention relates to a pharmaceutical composition comprising an antiviral compound selected from the group consisting of foscarnet, acyclovir, valaciclovir, penciclovir and famciclovir, in...
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6110955 |
Metabolically stabilized oxyalkylene esters and uses thereof
This invention relates to compositions for and methods of treating, preventing or ameliorating cancer and other proliferative diseases as well as methods of inducing wound healing, treating...
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6025363 |
Composition for suppressing appetite
A method for promoting appetite suppression without promoting anxiety, by administering at least one kavalactone and at least one methylxanthine. The compositions balance the energizing effects of...
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6020367 |
Supersaturated ascorbic acid solutions
A method of preparing a supersaturated and stable solution of ascorbic acid, supersaturated ascorbic acid solutions and compositions containing such supersaturated solutions. A polyol vehicle is...
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6001842 |
Compositions and methods for use in ischemia-reperfusion and endotoxin-related tissue injury
Methods of preventing or treating ischemia-reperfusion injury in an organ by administration of a composition containing a selective A 1 adenosine receptor antagonist and/or a P 2X purinoceptor...
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5981536 |
Use of xanthine derivatives for the modulation of apoptosis
Compounds of the formula I ##STR1## where one of the radicals R 1 and R 3 is a radical of the formula II --(CH 2 ) n --A--CH 3 (II) in which A is a covalent bond,--C(O)-- or --C(R 4 )(OH)--,...
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5977120 |
Composition for achieving an alert, yet calm state
Compositions and a method for promoting an alert state without promoting anxiety, comprising at least one kavalactone and at least one methylxanthine. The compositions balance the energizing...
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5972916 |
Compositions containing the nonprescription combination of acetaminophen, aspirin and caffeine to alleviate the pain and symptoms of migraine
The invention provides a safe and economical nonprescription combination of acetaminophen, aspirin and caffeine (APAP/ASA/CAF) for use in treating migraine pain and the cluster of symptoms...
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5945424 |
Treatment of periodic limb movement syndrome
The present invention is directed to a method for treating patients afflicted with periodic limb movement syndrome (PLMS) which includes administering to said patient prior to sleep a combination...
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5939423 |
Treatment of hepatitis B infection with thymosin alpha 1 and famciclovir
Treatment of hepatitis B virus (HBV) infection in a patient by administering to the patient a drug regimen including an antiviral-effective amount of thymosin alpha 1 (Tα1) and an...
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5900416 |
Aqueous caffeine dosage forms
Aqueous caffeine solutions containing a co-solubilizing agent selected from niacinamide, nicotinic acid and mixtures thereof present at a level up to the maximum concentration soluble in water and...
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5895649 |
Method for treating neurogenic red skin blotches with compositions containing TNF-alpha antagonists
Topically applicable pharmaceutical/dermatological/cosmetic compositions, well suited for the therapeutic treatment of neurogenic red skin blotches and rosacea afflicting the skin, scalp and/or...
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5871780 |
Pest-controlling composition
A pest-controlling composition comprised of a borate compound and a compound resulting in elevated concentrations of cyclic AMP, such as a phosphodiesterase enzyme (PDE) inhibitor, or a...
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5856330 |
Use of xanthine derivatives for the inhibition of dephosphorylation of cofilin
Compounds of the formula I ##STR1## where one of the radicals R 1 and R 3 is a radical of the formula II --(CH 2 ) n --A--CH 3 (II) in which A is a covalent bond, --C(O)-- or --C(R 4 )(OH)--,...
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5843452 |
Immunotherapy composition and method
A composition for use in immunosuppression therapy is disclosed. The composition includes an immunosuppressant drug, such as cyclosporin A, and an ethanol extract of the root xylem of Tripterygium...
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5760095 |
Method and system for effecting withdrawal from caffeine dependency
A method and system for effecting withdrawal from caffeine dependency is disclosed wherein the system comprises a regiment of dosage units having varying proportions of caffeine and an analgesic....
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5739139 |
Acetaminophen and dimenhydrinate analgesics
Disclosed are compositions comprising acetaminophen (APAP) and dimenhydrinate and methods for their use in analgesia. When acetaminophen and dimenhydrinate are within certain ratios, their...
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5667816 |
Pest-controlling compostion
A pest-controlling composition comprised of a borate compound and a compound resulting in elevated concentrations of cyclic AMP, such as a phosphodiesterase enzyme (PDE) inhibitor, or a...
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