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7417023 |
Targeted delivery of bioaffecting compounds for the treatment of cancer
A homogeneous conjugate for targeting and treating diseased cells wherein the conjugate comprises an anti-cancer drug and a targeting protein, wherein said anti-cancer drug is selected from the...
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7416893 |
Methods for diagnosing drug-resistant cancer cells or for identifying chemotherapeutic agents by measuring anomalous intracellular ion and/or second messenger dynamics
The present invention relates to methods of identifying drug-resistant and/or drug-sensitive cells, for example, breast cancer and brain tumor cells, on the basis of different ion and/or second...
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7416746 |
Method for cancer therapy using herbal extracts
A new method is described for the treatment of cancer. In one alternative, the method utilizes two main compositions. The first composition is Soma, a healing herb described in the Rig Veda, the...
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7415148 |
System and method for detecting anomalous targets including cancerous cells
A method and system for identifying anomalous cells includes an imaging subsystem to generate a track file from collected images of cells, a image processing subsystem to extract features from the...
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7414154 |
Polyamine compounds and compositions for use in conjunction with cancer therapy
The invention provides novel polyamine compounds and pharmaceutical compositions for administration in conjunction with cancer chemotherapy or radiation therapy. The compounds are administered...
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7413873 |
Method of detection and treatment of colon cancer
The present invention is based, in part, on the discovery that colon carcinoma, carcinogenesis, or the predisposition thereto is associated with the level of Wnt2, Wnt5, BMP6, and Fz receptors and...
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7413870 |
SAK: modulation of cellular proliferation for treatment of cancer
The present invention relates to regulation of cellular proliferation. More particularly, the present invention is directed to nucleic acids encoding SAK, which is a protein kinase involved in...
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7413864 |
Treating cancer using a telomerase vaccine
The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of...
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7412333 |
Method for prognostic factor analysis regarding cancers
A method for treating a patient with cancer includes the steps of obtaining cells from a cancerous tumor in the patient. Then there is the step of performing multiple correlated measurements on...
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7412285 |
Method and device for treating cancer with electrical therapy in conjunction with chemotherapeutic agents and radiation therapy
This invention relates generally to the electrical treatment of malignant tumors and neoplasms by applying a voltage to affected tissue. Devices and various adaptations therein are described for...
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7411046 |
Cancerous disease modifying antibodies
The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer...
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7410758 |
Methods and compositions relating to HPV-associated pre-cancerous and cancerous growths, including CIN
The present invention concerns the use of E6 and/or E7 peptides from human papilloma virus (HPV) to evaluate a cell-mediated response in a patient infected with HPV to determine the prognosis for...
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7410656 |
Anti-cancer compounds
This invention relates to a compound or group of compounds present in an active principle derived from plants of species Euphorbia peplus, Euphorbia hirta and Euphorbia drummondii , and to...
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7409243 |
Breast cancer detection
Apparatus for breast examination, comprising:
a sensing unit including a probe capable of sensing electrical signals from a surface of a breast, including at least a portion of the nipple...
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7408095 |
Methods for introducing heterologous cells into fish to determine if the heterologous cells contain cancer cells or a pathogen
Methods of introducing heterologous cells into fish are provided. After introduction cells remain viable, and in some instances proliferate, for sufficient time to conduct a variety of analyses on...
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7408046 |
Treatment of bone-associated cancers
The present invention relates to a method of suppressing bone marrow (BM) and treating conditions that arise in or near bone such as cancer, myeloproliferative diseases, autoimmune diseases,...
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7408022 |
Composition and method for increasing apoptosis in cancer cells
The invention provides cell permeable peptides and peptide agents that inhibit anti-apoptotic processes in cancer cells to promote tumor cell death, as well as a method for providing therapeutic...
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7407985 |
Compounds that abrogate DNA damage induced cell cycle G2 checkpoint and/or augment anti-cancer activity of DNA-damaging treatments
The invention provides compositions and methods to inhibit the cell cycle G2 checkpoint, in particular the DNA-damage-induced G2 checkpoint, in mammalian cells including human cells. Specifically,...
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7407759 |
Genetic alterations associated with prostate cancer
The present invention provides new probes for the detection of prostate cancer cells. The probes bind selectively with target polynucleotide sequences selected from the group consisting of 2q, 4q,...
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7407755 |
Determining a predisposition to cancer
The present invention relates to methods and kits for determining a predisposition and surveillance protocols for developing cancer of various sites due to specific mutation in at least one allele...
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7407673 |
Radioactive magnetic fluids for treatment or diagnosis of cancer, process for preparing them and use thereof
The present invention relates to radioactive magnetic fluids, process for preparing them and use thereof. Particularly, the present invention relates to the radioactive magnetic fluids for...
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7405314 |
Compounds and methods for the treatment of cancer
The present invention provides organic arsenicals. Many of these compounds have potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin,...
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7405309 |
Pyranone derivatives useful for treating cancer
The invention relates to pyranone derivatives of general formula (I), wherein X is chlorine, bromine or iodine and R 1 and R 2 is independently a hydrogen atom, an alkyl, cycloalkyl or alkylene,...
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7405290 |
Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer
A gene (designated 161P2F10B) and its encoded protein are described wherein 161P2F10B exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in the cancers listed in...
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7405287 |
Method of treating a cancer
The present invention provides isolated nucleic acids encoding delta DNA methyltransferase 3B molecules that are involved in the treatment and prevention of cancers such as, but not limited to,...
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7405227 |
Treatment of cancer
Methods of treating ovarian cancer, endometrium cancer, cervical cancer, pancreatic cancer, bladder cancer, eve cancer, central nervous system cancer, thyroid cancer and lung cancer are disclosed....
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7405200 |
Use of oxytocin for the preparation of a pharmaceutical composition against cancer in situ and cervicitis
A method of treating cancer in situ and cervicitis is disclosed. A pharmaceutical composition comprising at least one substance with oxytocin activity against cancer in situ and cervicitis and...
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7405077 |
Sperm protein 17 for the diagnosis and treatment of cancer
The results herein identify Sp17 as a novel cancer-testis antigen in multiple myeloma. Sp17 recombinant protein was generated from E. coli . A CD8 predominant CTL line was generated that was able...
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7402574 |
Antisense composition and method for treating cancer
A method and composition for treating colorectal cancer is disclosed. The method involves administering to a subject, a therapeutically effective amount of a morpholino antisense compound (i)...
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7402556 |
Prodrugs activated by plasmin and their use in cancer chemotherapy
The product of the invention is a modified form of a therapeutic agent and comprises a therapeutic agent, an oligopeptide having a plasmin peptide substrate of 2-4 amino acids and mono- or...
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7402402 |
P38 MAPK pathway predicts endocrine-resistant growth of human breast cancer and provides a novel diagnostic and treatment target
Acquired and de novo endocrine resistance are major clinical problems in the management of breast cancer patients. Though the antiestrogen tamoxifen prolongs disease-free and overall survival in...
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7402389 |
Compositions and methods for prognosis of cancers
The present invention provides compositions and methods of using the EPHB2 gene or its related signaling pathways to detect, prognosticate, assess the risk of, prevent, or treat cancers. Cancers...
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7402388 |
Expression analysis of FKBP54 in assessing prostate cancer therapy
The invention relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating prostate cancer. FKBP markers are provided, wherein changes in the levels of...
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7402317 |
Anti-cancer vaccine
There is disclosed a method of preparing a vaccine suitable for administration to humans for the prevention or treatment of cancer. The vaccine is prepared by culturing human cancer cells in a...
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7402307 |
Method for identifying and killing cancer cells
The invention provides a method for activating a T lymphocyte by contacting the T lymphocyte with a dendritic cell (DC) that presents a telomerase reverse transcriptase (TRT) peptide in the context...
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7402306 |
Cancer immunotherapy with semi-allogeneic cells
The present invention relates to improved semi-allogeneic immunogenic cells which act to stimulate and induce an immunological response when administered to an individual. In particular, it relates...
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7399835 |
Cancerous disease modifying antibodies
The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer...
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7399787 |
Methods of treating cancer with HDAC inhibitors
The present invention provides methods of treating cancers, chemoprevention, selectively inducing terminal differentiation, cell growth arrest and/or apoptosis of neoplastic cells, and/or...
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7399469 |
Anti-LFL2 antibodies for the diagnosis, prognosis and treatment of cancer
Particular anti-LFL2 antibody compositions are provided herein. These antibodies may be used for diagnosis, prognosis, therapeutic monitoring and treatment of cancer, especially breast cancer,...
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7396810 |
Compositions and methods for treating cancer by modulating HER-2 and EGF receptors
An alternative HER-2/neu product, herstatin, consists of subdomains I and II from the ectodomain of p185HER-2 and a unique 79 amino acid C-terminus encoded by intron 8. Recombinant herstatin added...
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7396666 |
Glycosyltransferase, nucleic acid encoding the glycosyltransferase and method of testing canceration using the nucleic acid
A tumor marker nucleic acid of the present invention is concerned with a nucleic acid hybridizing under stringent conditions to a nucleotide sequence described in SEQ ID NO: 1 or a complementary...
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7393869 |
Methods of using thiazolidine derivatives to treat cancer or inflammation
Methods of using thiazolidine derivatives of formula (I) to treat cancer, inflammation, or other disorders related to the activities of protein phosphatases PTPN12 or PTPN2 in a mammal are...
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7393685 |
Method for cultivating cancer cells from human tissue and device for preparing tissue samples
The invention relates to a method for cultivating cancer cells for scientific serial assays, wherein a tissue sample which is heterogeneous with respect to contaminants, normal cells and tumor...
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7393657 |
Diagnosis and treatment of cancer: I
A method of diagnosing cancer comprising the steps of (i) obtaining a sample containing nucleic acid and/or protein from the patient; and (ii) determining whether the sample contains a level of...
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7393637 |
Methods for detecting cancer and monitoring cancer progression
Mutant BNIP3 plays a functionally important role in the development of solid tumors and in resistance to chemotherapy and radiation treatments. The invention relates to methods of detecting cancer,...
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7393534 |
Compositions and methods for immunotherapy of cancer and infectious diseases
The present invention provides compositions and methods for the prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases, for stimulating an immune response in...
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7393527 |
Method for limiting the growth of cancer cells using an attenuated measles virus
A method for treating cancer cells is provided comprising directly or systemically administering a therapeutically effective dose of an attenuated measles virus. In one embodiment, the...
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7393478 |
Therapy for human cancers using cisplatin and other drugs or genes encapsulated into liposomes
A method for encapsulating cisplatin and other positively-charged drugs into liposomes having a different lipid composition between their inner and outer membrane bilayers is disclosed. The...
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7390915 |
Phosphine transition metal complex having ferrocene skeleton, process for making the same, and anti-cancer agent
An anti-cancer agent contains a phosphine transition metal complex having a ferrocene skeleton, the complex being represented by general formula (3) below:
(wherein R 1 , R 2 , R 3 , and R...
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7387895 |
Monoclonal antibody specific for PPAR gamma, hydridoma cell line producing the same, and method for detecting regulator related to diseases, including inflammation, cancer and metabolic diseases, using the same
The present invention relates to a hybridoma cell line producing a PPAR gamma-specific monoclonal antibody, and a method for detecting a PPAR gamma ligand related to the progression of difficult...
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